Working Volume: 15 L to 50 L;Stainless Steel
Model: BioTwin
Order NO.: BioTwin
143
Specific parameters will be adjusted according to product upgrades, without notice.
Compact Design controls 1 or 2 vessels.
Compatible with 15L to 50L stainless steel vessels.
Upgradable from a single-vessel to a dual-vessel configuration.
Unique Design
Stylish design which complies to all laboratory requirements, Possible upgrade from one vessel to a two vessel BioTwin.
15 "touch screen
A touch screen controller that meets industrial standards and has an IP 65 protection level.
Proprietary software
Hierarchical permission management, meeting the requirements of shared and secure data storage among
multiple departments.
Open Systems
Replenishment: 1-5 Peristaltic pump can be configured as required, or more Peristaltic pump can be integrated externally.
Air circuit: Add MFC, rotameter, or manual valve as needed.
Powerful and scalable features.
User-friendly design
Designed according to the experimenter's operating habits, the entire system is flexible and easy to operate, maintain,
and repair, saving laboratory work.
Export Data
Export data and graphs, including set and actual values, to ensure data integrity.
BioTwin bioreactor, vessel size from 15L to 50L
Control cabinet
BioTwin controller adopts a new PLC level touch screen design, and the detection sensor receives the signal transmission,
including 20 analog and 10 digital signal input channels such as temperature, stirring, pH, pO2, Redox, liquid level, gas flow,
pressure control, biomass, current and voltage standard signals. In addition, there are 12x analog signals, 24x digital signals
and, 32x Modbus for connecting drive and control expansion units, which can also be connected to monitoring software
through OPC protocol.
Data recording&process control
Each control loop is independent and adopts modular design for flexible operation. Users can modify parameters according
to application requirements to fine tune the control strategy.
Each parameter can be separately monitored (measuring range, calibration), controlled (set value, upper and lower limits
of alarm, rule regulation, signal output, PID control data, digital and analog signal output) and set for remote control.
Tubing Design
To ensure long-term operation under aseptic conditions, Techfors pipeline design has the following characteristics:
The piping process adopts no dead corner welding to ensure that it can still work under aseptic conditions after long-term use.
The valves in contact with the medium are diaphragm valves.
Two steam circuits, one for process control and the other for maintenance and repair. If necessary, two different quality steam
can be used for both circuits.
Two separate condensate drainage pipelines meet the requirements of relevant laws and regulations on sewage treatment.
The inlet and outlet connectors are made of stainless steel and installed on the back of the bracket for later maintenance.
The design of an open stainless steel bracket and movable roller is convenient for movement, installation and maintenance.
Open water loop temperature control
Fully automatic cooling/heating/sterilization system.
Temperature control through feeding cold or chilled (automatic) water directly into the double jacket and heating through the feed of steam into a heat exchanger. Safety is ensured through the use of a safety valve that has been tested by a specialist manufacturer. Condensate leaves via steam traps and a separate line with a circulation system. Water entry into the exit gas cooler is via an in-line pressure regulator. Switching either on or off is controlled. Incl. automatic switchable between tap and chilled water
Flexible Software-Based Sterilization Program Configuration
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Active sequence |
Activationpossible? |
1 | 2 | 3 | 4 | 5 | 6 |
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Fermentation |
1 |
x |
f r |
YES |
YES |
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Medium Sterilization |
2 | ![]() |
x |
YES |
YES |
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Sterilization Sample Valve |
3 |
YES |
YES |
x |
YES |
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Sterilization addition line |
4 |
YES |
YES |
YES |
x |
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Pressure test |
5 | ![]() |
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x |
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Clean in place |
6 | |
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x |
Legenda compatibiltiy chart
=Simultaneous action prohibited |
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YES =Simultaneous action possible |
BOS control software
Different permissions meet the requirements of hierarchical management.
It can focus on the running projects in real time: it can be accessed through the connection between the LAN and the vessel and can be browsed by the client. It can be accessed remotely through Apps. A set of BOS software can realize the joint management of Biostream products.
Specifications
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Controller |
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Design |
Multi touch 15 inch screen with a separate PC Capable of communicating with 32 utility stations each a separate vessel. |
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Function |
Monitoring (data storage) and control |
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Agitation |
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Drive |
Depends on vessel |
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Stirrer speed |
Speed is adjustable between 50-800 RPM |
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Control |
PID control |
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Volume specification |
15/10L,29.5/20 L,50/35L |
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Temperature |
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Range |
Water jacket vessel:above coolant (>0°C) from around 5°C above room temp to 130 °C. |
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Sensor |
Pt-100 sensor (vessel and water system) |
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Accuracy |
+/- 0.1℃ in range +10°to +60℃ in fluids. |
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Control |
PID control |
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Tempe. security |
Automatic safety thermostat |
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pH |
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Range |
2-14 |
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Control |
PID. Base and Acid (or CO2 gas) addition to control pH. Setting of dead band |
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Accuracy |
+/- 0.01 |
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Sensor |
Mettler or Hamilton |
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DO Control Unit |
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Range |
0 -150 % |
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Control |
PID |
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Sensor |
Mettler or Hamilton |
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Exhaust condenser |
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Standard 0,2 μm PALL filter (also other options available) |
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Integrated Pumps |
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Standard Configuration: 3 digital pumps (for base, acid, and antifoam) and 2 optional analog pumps (for feeding). Each pump can be switched between digital and analog control modes. Additional integrated or external pumps can be supplied and freely configured on the control panel. Optional: Watson Marlow peristaltic pump with a pumping speed of 78 ml/min. |
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Gas mix |
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Each gas is equipped with a pressure reducing valve and a pressure gauge, and you can customize your gas configuration scheme: Air,O2 ,N2,CO2 and more gases Flowmeter:rotameters,mass flow controllers,Solenoid valve or manual switch (flexible application and calibration) |
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Utilities |
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power supply:380V/50Hz ≥4 bar oil free gasses ≥2.5 bar water (normal tap water pressure) |
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Aux. equipment |
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All kinds of external measurements can be integrated in the touch screen. |
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Power |
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220 V; 5 Amp |
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Extended functions |
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0-10V, 4-20mA, 24Volt, Modbus, CAN Bus, RS-232 |
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Option validation package |
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Factory Acceptance Test (FAT at Biostream) Site Acceptance Test (SAT at Customer) Installation Qualificiation (IQ) Operational Qualification (OQ) |
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