Unique Design

Stylish benchtop design built from scratch. Different colors on the cover to customize the design LED light adjustable. Complies to all laboratory requirements.  

 

12" Touchscreen

Intuitive and advanced control of up to 6 BioBenches at a time.  Touch screen is moveable. Unit can also be used without a touchscreen, controlled from a computer

 

Proprietary Software

Developed by Biostream software engineers. Integration of instruction movies and protocols. Easy adaptation for your specific needs.

High Customizability

1 – 5 Pumps integrated and more pumps outside the unit.

Mass flow controllers, rotameters and valves for adding gasses and fluids.

 

User Friendly

Short cables for pH, DO, antifoam and temperature sensors can be quickly plugged in thanks to easy connectors. Plug and play mode for your vessel.

 

Data Export

Multiple options for data export, including used parameters and setpoints.

 

Motor

Mechanical or magnetic drive system for stirrer.

Biobased motor with torque measurement.

Motor can be placed on mount on top of the controller when not in use.

 

Pump Configuration

Anywhere from 1 up to 5 Watson Marlow peristaltic pumps integrated.

External extra pumps easily connectable.

Free configurable for feed, base, acid, antifoam and more.

 

Flow Control

Complete flexible gas mix control with mass flow controllers, rotameters and valves for adding gas/fluids.

*Multi gas mixing station (provide mixing of N2, O2, CO2 and air in cell culture)

 

Accessory equipment

*Redox measuring system for measuring redox potential

*External simulated peristaltic pump provides variable rate feeding.

*Glucose analyzer

*Tail gas analyzer

*Pressure measurement and control system0

*Refrigeration equipment

*External balance weighing equipment

 

Tubing Design

To ensure long-term operation under aseptic conditions, Biobench pipeline design has the following characteristics:

The piping process adopts no dead corner welding to ensure that it can still work under aseptic conditions after long-term use.

The valves in contact with the medium are diaphragm valves.

One steam circuits, for process control. The inlet and outlet connectors are made of stainless steel.

 

Open water loop temperature control

Fully Automated Heating / Cooling / Sterilization System
Temperature is controlled by direct circulation of cooling water through the vessel jacket for cooling, and by introducing steam into the heat exchanger for heating. All valves are tested post-installation to ensure safety and reliability. Condensate is automatically discharged through steam traps and a dedicated recirculation pipeline. Valve operation throughout the system is fully automated.

Vessel specification

Total Volume	7.5 L	10 L	15 L
Working volume	1.5-5 L	2.5-7 L	2.5-12 L
Type op ports (standard)
10 mm	5	5	5
12 mm (PG13,5),	8	8	8
19 mm	1	1	1
Head plate is free configurable with more ports
Impellers
Microorganism:
Rushton impellers (0,33 ID)	3	3	3
Cell culture:
Marine impeller (0,5 ID)	2	2	2
Different Impellers and accessories can be customized according to user needs
Vessel type	Stainless steel double jacket vessel

 

Extended Capabilities
Online Redox Sensor

Measurement range: –1000 mV to 1000 mV

Pressure range: ≤2.5 bar

Temperature range: 0–135 °C

Sterilization compatibility: Supports up to 100 sterilization cycles under standard conditions

Diameter: 12 mm

Optical Density (Optek)

Single-channel near-infrared (NIR) sensor

Wavelength range: 840–910 nm

Materials

Liquid-contact components: Stainless steel 1.4435 (SS 316L)

Connection Interface

Vessel lid port: 12 mm / PG 13.5

Autoclavable (without cable)

Physical Dimensions

Optical path length (OPL): 5 mm

Insertion depth: 220 mm

Online CO₂ Sensor (Mettler Toledo)
Dissolved CO₂ is a naturally occurring cytotoxic byproduct in cell culture. Elevated dissolved CO₂ levels can lead to undesirable metabolic shifts, suppressed cell growth, and reduced productivity. The Mettler Toledo InPro® 5000 CO₂ sensor enables real-time analysis of CO₂ concentration during bioprocessing, allowing rapid response and potentially increasing cell growth rates by up to 30%.

Exhaust Gas Analyzer (Blue In One)

Concentration ranges:0.1–25% O₂ / 1–50% O₂；0–10% CO₂ / 0–25% CO₂Real-time

Measurement of CO₂, O₂, pressure, and humidity Indirect calculation of: Oxygen uptake rate (OUR)；Carbon dioxide evolution rate (CER)；Respiratory quotient (RQ)；Includes automatic pressure compensation

Solid Feeding System

Independent feeding unit connected via a 19 mm port on the vessel lid

The drive motor for solid feeding operates similarly to those used for acid/base/antifoam pumps and can be controlled via software for ON/OFF operation and feed rate adjustment

Solids are stored in a sealable funnel-type reservoir, which can be sterilized together with the vessel

Solid Feeding System
An independent feeding unit connected via a 19 mm port on the vessel lid.
The drive motor for solid feeding operates similarly to those used for acid/base/antifoam feed pumps, enabling software-based ON/OFF control and adjustable feeding rates.
Solids are stored in a sealable funnel-type reservoir, which can be sterilized together with the vessel.

Balance
Balances with various weighing capacities are available to accommodate different vessel volumes and experimental requirements.

Pressure Monitoring and Control System (Safety-rated Protection)

Pressure range: 0.5–10 bar

Linearity: Type ±0.2% FS, ±0.5% FS

Stability: Type 0.1% FS, 0.2% FS

Operating temperature: –20 to 150 °C

Proportional valve with magnetic body: 316L

Sealing: FPM (Fluoroelastomer)

Ambient temperature: ≤55 °C

Spin Filter (for Cell Culture)

12–15 μm pore size for suspension cell culture

75 μm pore size for microcarrier-based culture

An internal dip tube enables cell-free medium harvesting.

Glass Vessel Overpressure Protection Device
Depending on the application, a rupture disk can provide additional overpressure protection during operation. The disk is clamped between two pipe sections using a tri-clamp connection. One pipe end features a vent port for installation into a designated port on the fermenter top plate; the other end has a flange for connection to a safe discharge line.